Diosmin and Hesperidin are flavonoids with phlebotonic and vascular-protective effects. They enhance venous tone by sustaining norepinephrine activity on the vessel walls, thus reducing venous capacity, distensibility, and emptying time.
These compounds protect microcirculation by preventing inflammation-related damage, reducing leukocyte activation, and limiting the release of harmful agents like free radicals and prostaglandins. This results in improved capillary resistance and reduced permeability.
They also promote better lymphatic drainage, increasing lymph flow and oncotic pressure, which supports overall vascular health.
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Normanal DS is a combination therapy primarily used to treat varicose veins and associated venous disorders. It enhances blood flow and helps restore proper venous function. The medication can be taken with or without meals, as per your doctor’s direction. It’s important to complete the full course, even if symptoms improve early—stopping too soon may lead to a return or worsening of symptoms
Each DS (Double Strength) tablet contains:
Normanal DS is a flavonoid formulation that reduces inflammation by inhibiting inflammatory mediators like prostaglandins and thromboxane A2. This action helps to ease vein swelling, improve circulation, and restore proper vein function.
No significant drug interactions have been identified in clinical trials.
Known hypersensitivity to any ingredient in the formulation.
Diagnosis and management of venous insufficiency should be done under medical supervision.
Inform your doctor if you have heart, liver, or kidney disease.
Pregnant and breastfeeding women should seek medical advice before using this medicine.
If hemorrhoidal symptoms persist beyond 15 days, seek further medical evaluation.
Not advised for patients with a history of cancer due to a lack of specific studies, despite no evidence of carcinogenicity from long-term European usage.
Animal studies have shown no teratogenic risks; however, the lack of data on breast milk excretion means breastfeeding is not recommended during treatment.
Acute Hemorrhoids: 1 tablet three times daily for 4 days, then 1 tablet twice daily for 3 days; maintenance: 1 tablet daily.
Recurrent or Chronic Hemorrhoids: 1 tablet daily for 3 months.
Venous Insufficiency: 1 tablet daily for 2–6 months.
Leg Ulcers: 1 tablet daily for 2 months.
Tablets should be taken with meals.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.